Contents Of This Article
- Cannabidiol lowers blood pressure
- Cannabidiol (CBD) supplements
- Best cannabidiol supplements
- Cannabidiol side effects
Cannabidiol lowers blood pressure
Cannabidiol (CBD) supplements are increasingly used as an herbal supplement to generate feelings of well-being and to increase the ability to cope with anxiety and stress.
In a small trial, 9 healthy male volunteers were given breakfast and, 15 minutes later, took either a CBD capsules (providing a relatively high dose of 600mg cannabidiol) or placebo, without knowing which was which. This was repeated on separate occasions, to compare the effects of CBD against placebo on their resting blood pressure and how they responded to various types of stress:
- mental stress, which involved calculating an arithmetic sum every 2 second for 2 minutes
- exercise stress, in which they had to grip a hand dynamometer at 30% maximum strength for 2 minutes
- cold stress, in which they immersed their left foot, up to the ankle, in ice slush at a temperature of 4°C to 6°C for 2 minutes.
When the men took the active cannabidiol (CBD) dose, their resting systolic blood pressure fell significantly by an average of 6/3 mmHg, compared with placebo. When subjected to stress, those who had taken CBD also had a 5 mmHg lower blood pressure before and after mental stress, a systolic blood pressure that was 5 mmHg lower before and after exercise stress, and a systolic blood pressure that was 8 mmHg lower before and after cold stress.
As well as lowering blood pressure, there was an associated lower stroke volume (amount of blood pumped from the heart per beat) and a higher heart rate, especially during the post-test periods.
The researchers suggest these findings are due to the anti-anxiety and analgesic effects of cannabidiol (CBD) and may also show direct, beneficial cardiovascular effects in relaxing blood vessels.
Cannabidiol (CBD) supplements
Cannabidiol extracts are typically combined with olive oil, coconut oil or hemp seed oil to enhance absorption. They are available as capsules, gummies, drops and oral sprays.
Always follow manufacturer’s guidance on how much of their product to take, which will vary depending on concentration.
For general well-being the recommended dose is usually 10mg to no more than 200mg per day as a food supplement.
Products typically supply 6mg to 25mg CBD per serving.
NB The dose (600mg) used in this clinical trial was a medicinal therapeutic dose that is significantly higher than the doses found in supplements to promote well-being, relaxation and improve sleep.
Do not take high doses except under medical supervision.
If you are taking antihypertensive medication check with a doctor or pharmacist before using cannabidiol (CBD).
Best cannabidiol supplements
If you don’t mind the strong herbal flavour, then you can take cannabidiol as drops, a spray or as gummies. If you prefer to take cannabidiol in the form of an Oil, then Endoca offer two strengths of pharmaceutical-grade cannabidiol in capsules which are easy to take:
- High strength CBD oil (300mg cannabidiol) with added olive oil to aid absorption.
- Super Strength CBD Oil (1500mg cannabidiol ) with added food grade hemp oil to increase absorption.
These are a perfect introductions to cannabidiol.
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In a recent report, the World Health Organisation confirmed that cannabidiol does not have any potential for causing physical dependence, withdrawal symptoms or tolerance (in which increasing doses would be needed – a phenomenon known as tachyphylaxis) and that cannabidiol is not associated with any potential for abuse. This has reassured many doctors that, in recommended doses for wellbeing, it is safe to use to aid relaxation and to offset the adverse effects of stress.
Many small studies suggest that cannabidiol (CBD) is well tolerated with no significant side effects at usual doses. Cannabidiol CBD oil has beneficial effects on relaxation and well-being without producing a ‘high’.
Cannabidiol side effects
The high doses used in the above study should only be used under medical supervision, but small doses (eg 15mg twice a day) may help to reduce a stress-related raised blood pressure.
In clinical trials, commonly reported side effects with high doses of cannabidiol include sleepiness, diarrhoea, and changes in appetite.
NB. Do not take high doses of cannabidiol if you are on antihypertensive medication, as interactions can occur – CBD reduces the metabolism of certain drugs within the liver by inhibiting the effect of cytochrome P450 enzymes. This may slow the metabolism of some pharmaceutical drugs, leading to higher than normal blood levels.
If in doubt, always seek medical advice.
|Cannabidiol used as a food supplement is legal within the UK & USA and some other countries, as long as manufacturers do not make medical claims.|